Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14641136 | 0.87 | POLA1 (0.53) | POLA1CYP46A1PLA2G2A | |
| SCHEMBL13391627 | 0.87 | POLA1 (0.53) | POLA1CYP46A1PLA2G2A | |
| SCHEMBL14602524 | 0.87 | POLA1 (0.53) | POLA1CYP46A1PLA2G2A | |
| SCHEMBL9885952 | 0.87 | POLA1 (0.51) | POLA1CYP46A1 | |
| SCHEMBL15256420 | 0.85 | POLA1 (0.50) | POLA1CYP46A1PLA2G2A | |
| SCHEMBL16683692 | 0.85 | POLA1 (0.50) | POLA1CYP46A1PLA2G2A | |
| SCHEMBL15255868 | 0.85 | POLA1 (0.50) | POLA1CYP46A1PLA2G2A | |
| SCHEMBL140321 | 0.84 | POLA1 (0.70) | POLA1CYP46A1PLA2G2A | |
| SCHEMBL412985 | 0.84 | POLA1 (0.70) | POLA1CYP46A1PLA2G2A | |
| SCHEMBL767706 | 0.84 | POLA1 (0.70) | POLA1CYP46A1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349415-B2 | Liquid-crystalline medium and liquid-crystal display having high twist | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20110315924-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY HAVING HIGH TWIST | MERCK PATENT GMBH MIT BESCHRAENKTER HAFTUNG (DD) | 2011-12-29 | — | — | US | disclosed |