Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036681 | 0.87 | POLA1 (0.49) | POLA1CYP46A1 | |
| SCHEMBL27320857 | 0.82 | POLA1 (0.75) | POLA1CYP46A1 | |
| SCHEMBL27320877 | 0.82 | POLA1 (0.75) | POLA1CYP46A1 | |
| SCHEMBL11423844 | 0.82 | POLA1 (0.75) | POLA1CYP46A1 | |
| SCHEMBL11426770 | 0.82 | POLA1 (0.75) | POLA1CYP46A1 | |
| SCHEMBL28088866 | 0.82 | POLA1 (0.75) | POLA1CYP46A1 | |
| SCHEMBL27320821 | 0.82 | POLA1 (0.75) | POLA1CYP46A1 | |
| SCHEMBL27883156 | 0.82 | POLA1 (0.75) | POLA1CYP46A1 | |
| SCHEMBL8608992 | 0.82 | POLA1 (0.75) | POLA1CYP46A1 | |
| Ethane SCHEMBL27501171 | 0.82 | POLA1 (0.74) | POLA1CYP46A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193246-B2 | Lipids and lipid assemblies comprising transfection enhancer elements | MARINA BIOTECH, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-8193246-B2 | Lipids and lipid assemblies comprising transfection enhancer elements | MARINA BIOTECH, INC. (US) | 2012-06-05 | — | — | US | disclosed |