SCHEMBL412985

SCHEMBL412985

CCCCCCCCCCCCCCCC(=O)OC1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]32)C1

nearest known ligand 0.84

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ POLA1 P09884 1/20 0.70
▸ CYP46A1 Q9Y6A2 2/20 0.69
▸ USP2 O75604 2/20 0.65
▸ LMNA P02545 1/20 0.65
▸ ABCB1 P08183 1/20 0.65
▸ OSBP P22059 1/20 0.65
▸ RORC P51449 1/20 0.65
▸ OSBP2 Q969R2 1/20 0.65
▸ PLA2G2A P14555 1/20 0.62
▸ NPC1 O15118 1/20 0.59
▸ NR1H3 Q13133 2/20 0.58
▸ NPC1L1 Q9UHC9 1/20 0.58
▸ GBA1 P04062 2/20 0.58
▸ UGCG Q16739 2/20 0.58
▸ GBA2 Q9HCG7 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190539 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL161747 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL767706 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL162885 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL22620094 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL21177689 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL140321 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL18006649 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL295638 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL9436821 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 906 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12233034-B2 Formulations for epidermal repair CLARIDEI LABORATORIES, INC. (US) 2025-02-25 — — US claimed
CN-119499247-A Double-drug-carrying recombinant high-density lipoprotein nanoparticle for improving or treating intestinal inflammation and preparation method and application thereof 中国农业大学 2025-02-25 — — CN claimed
CN-118141908-A Lymph targeting tumor nano vaccine and application thereof 中国药科大学 2024-06-07 — — CN claimed
CN-117597118-A Pharmaceutical composition for preventing or treating viral infection comprising as active ingredient a crude drug QVET公司 2024-02-23 — — CN claimed
CN-117098536-A Composition containing antitumor drug and preparation method and application thereof 昆山新蕴达生物科技有限公司 2023-11-21 — — CN claimed
WO-2023061393-A1 COMPOSITION CONTAINING ANTITUMOR DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF 昆山新蕴达生物科技有限公司 2023-04-20 — — WO claimed
CN-115919771-A Reverse phospholipid liposome assembly and preparation method thereof 于喜飞 2023-04-07 — — CN claimed
CN-115461096-A Polymer encapsulated drug particles 吉益医疗公司 2022-12-09 — — CN claimed
EP-4025660-A1 THERMOCHROMIC LIQUID CRYSTAL INKS AND COATINGS Sun Chemical Corporation (US) 2022-07-13 — — EP claimed
CN-114526968-A Preparation and use method of skin bionic dirt 北京颐唯实检测技术有限公司 2022-05-24 — — CN claimed
EP-0797433-A1 GAS FILLED MICROSPHERES AS MAGNETIC RESONANCE IMAGING CONTRAST AGENTS ImaRx Pharmaceutical Corp. (US) 1997-10-01 — — EP claimed
EP-0760684-A1 GAS FILLED MICROSPHERES AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX PHARMACEUTICAL CORP. (US) 1997-03-12 — — EP claimed
EP-0740528-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1996-11-06 — — EP claimed
WO-1995032006-A1 GAS FILLED MICROSPHERES AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX, PHARMACEUTICAL CORP. (US) 1995-11-30 — — WO claimed
WO-1995024184-A1 GAS FILLED MICROSPHERES AS MAGNETIC RESONANCE IMAGING CONTRAST AGENTS UNGER EVAN C (US) 1995-09-14 — — WO claimed
WO-1995015118-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1995-06-08 — — WO claimed
EP-0367788-A1 RECEPTOR-BASED BIOSENSORS ARTHUR D. LITTLE, INC. (US) 1990-05-16 — — EP claimed
WO-1988009808-A2 RECEPTOR-BASED BIOSENSORS ARTHUR D. LITTLE, INC. (US) 1988-12-15 — — WO claimed
US-4397839-A RESPIRATORY DISTRESS SYNDROME TOKYO TANABE COMPANY, LIMITED (JP) 1983-08-09 — — US claimed
US-4011138-A FERMENTATION OF PSEUDOMONAS KYOWA HAKKO KOGYO CO., LTD. (JA) 1977-03-08 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12233034-B2 Formulations for epidermal repair KRT18, CUTA, DSG1 POLA1 2900/4885CYP46A1 1451/4885USP2 1927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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