Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036708 | 0.94 | BRD2 (0.38) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL12036709 | 0.89 | NPC1 (0.44) | HTR7HTR1ABRD4BRD2BRD3 | |
| SCHEMBL12036703 | 0.77 | HTR7 (0.36) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL12036706 | 0.73 | HPGD (0.36) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL14920698 | 0.72 | NPC1 (0.46) | HTR1AHSD17B3LMNANPC1RAB9A | |
| SCHEMBL14933489 | 0.71 | NPC1 (0.45) | HTR1ALMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14933594 | 0.70 | TYRO3 (0.44) | HSD17B3LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12036704 | 0.70 | FABP4 (0.32) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL14933445 | 0.69 | UGCG (0.46) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL14933595 | 0.69 | TYRO3 (0.36) | HSD17B3MGLLLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085579-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-21 | — | — | US | disclosed |
| US-9085579-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-21 | — | — | US | disclosed |
| US-20110315933-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20110315933-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| WO-2010102709-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110315933-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EPCAM, L1CAM, VCL | PDE6D 1971/4885HTR7 4444/4885HTR1A 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.