SCHEMBL120379

SCHEMBL120379

COc1cc(OCCCC(=O)O)ccc1CO

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DHFR P00374 1/20 0.48
▸ FFAR1 O14842 5/20 0.48
▸ FFAR4 Q5NUL3 5/20 0.48
▸ TSHR P16473 1/20 0.46
▸ PPARG P37231 1/20 0.45
▸ PPARD Q03181 1/20 0.45
▸ PPARA Q07869 1/20 0.45
▸ PTPN1 P18031 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402124 1.00 DHFR (0.48) DHFRFFAR1FFAR4TSHRPPARG
SCHEMBL1229002 0.96 DHFR (0.53) DHFRFFAR1PPARGPPARDPPARA
SCHEMBL2046234 0.94 PPARA (0.52) DHFRFFAR1PPARGPPARDPPARA
SCHEMBL30215712 0.89 CD274 (0.46) DHFRFFAR1
SCHEMBL16301494 0.89 PDE3B (0.43) FFAR1
Aminodiphenylmethane SCHEMBL1963354 0.88 NR1H3 (0.46) DHFRFFAR1FFAR4PTPN1
SCHEMBL17593842 0.87 DHFR (0.50) DHFRFFAR1FFAR4TSHRPPARG
SCHEMBL10335441 0.85 LMNA (0.53) DHFRFFAR1FFAR4TSHRPPARG
SCHEMBL12036216 0.85 CNR1 (0.48) —
SCHEMBL5953370 0.84 FFAR1 (0.45) DHFRFFAR1FFAR4TSHRPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378267-B2 Synthesis of FMOC-protected morpholino monomers and oligomers ENTRADA THERAPEUTICS, INC. (US) 2025-08-05 — — US claimed
US-20230097585-A1 SYNTHESIS OF FMOC-PROTECTED MORPHOLINO MONOMERS AND OLIGOMERS ENTRADA THERAPEUTICS, INC. 2023-03-30 — — US claimed
EP-3405476-B1 METHOD FOR PREPARATION OF PEPTIDES WITH psWANG LINKER POLYPEPTIDE LABORATORIES HOLDING PPL AB (SE) 2022-05-18 — — EP claimed
US-11236123-B2 Method for preparation of peptides with psWang linker POLYPEPTIDE LABORATORIES HOLDING (PPL) AB (SE) 2022-02-01 — — US claimed
CN-104619717-B The synthesis of β-corner simulation peptide cyclic compound 米梅奥亨制药公司 2019-04-02 — — CN claimed
US-20180259510-A1 NON-COVALENT PATTERNED CHEMICAL FEATURES AND USE THEREOF IN MALDI-BASED QUALITY CONTROL NATIONAL SCIENCE FOUNDATION 2018-09-13 — — US claimed
US-20160041158-A1 NON-CONVALENT PATTERNED CHEMICAL FEATURES AND USE THEREOF IN MALDI-BASED QUALITY CONTROL NATIONAL SCIENCE FOUNDATION 2016-02-11 — — US claimed
CN-104619717-A Synthesis of beta-turn peptidomimetic cyclic compounds MIMETOGEN PHARMACEUTICALS INC 2015-05-13 — — CN claimed
WO-2014144383-A1 NON-COVALENT PATTERNED CHEMICAL FEATURES AND USE THEREOF IN MALDI-BASED QUALITY CONTROL ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-09-18 — — WO claimed
JP-4625603-B2 — — 2011-02-02 — — JP claimed
US-20020173051-A1 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY 2002-11-21 — — US claimed
WO-2002081078-A2 SOLID PHASE SYNTHESIS SUPPORTS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-10-17 — — WO claimed
EP-1214336-A1 SYNTHESIS OF TEMPLATE-FIXED BETA-HAIRPIN LOOP MIMETICS Universität Zürich (CH) 2002-06-19 — — EP claimed
WO-2002000337-A1 A CHROMATOGRAPHY MATERIAL AND A PROCESS OF MANUFACTURING THAT MATERIAL BIA SEPARATIONS D.O.O. (SI) 2002-01-03 — — WO claimed
WO-2001016161-A1 SYNTHESIS OF TEMPLATE-FIXED β-HAIRPIN LOOP MIMETICS Universität Zürich (CH) 2001-03-08 — — WO claimed
EP-1018526-A1 Process for preparing polyurethane foam CK WITCO CORPORATION (US) 2000-07-12 — — EP claimed
EP-0929567-A1 IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS Zealand Pharmaceuticals A/S (DK) 1999-07-21 — — EP claimed
US-5858534-A FOR SOLID PHASE SYNTHESIS; POLYSTYRENE COATED METAL OXIDE PARTICLES DISPERSED IN POLYSTYRENE MATRIX SOLID PHASE SCIENCES CORP. (US) 1999-01-12 — — US claimed
WO-1998011125-A1 IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS ZEALAND PHARMACEUTICALS A/S (DK) 1998-03-19 — — WO claimed
EP-0608779-A1 Apparatus for peptide synthesis SHIMADZU CORPORATION (JP) 1994-08-03 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173051-A1 Solid phase synthesis supports and methods FES, LSS, CCNK DHFR 1700/4885FFAR1 3857/4885FFAR4 3631/4885
US-12378267-B2 Synthesis of FMOC-protected morpholino monomers and oligomers PMM2, PHAX, PTBP3 DHFR 1130/4885FFAR1 3944/4885FFAR4 4008/4885
US-11236123-B2 Method for preparation of peptides with psWang linker VIP, GLP1R, IAPP DHFR 2354/4885FFAR1 932/4885FFAR4 645/4885
US-20230097585-A1 SYNTHESIS OF FMOC-PROTECTED MORPHOLINO MONOMERS AND OLIGOMERS PMM2, PHAX, PTBP3 DHFR 1130/4885FFAR1 3944/4885FFAR4 4008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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