SCHEMBL1204264

SCHEMBL1204264

CCCCCCCCc1ccc2ccccc2c1O

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.54
LIPG Q9Y5X9 1/20 0.49
KDM4E B2RXH2 1/20 0.48
USP2 O75604 1/20 0.48
ALDH1A1 P00352 1/20 0.48
GLA P06280 1/20 0.48
CYP3A4 P08684 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
CASP1 P29466 1/20 0.48
CASP7 P55210 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28595564 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL10353654 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL11339331 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL9456682 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL25199957 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL9456573 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL25205081 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL8974340 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL11134384 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1
SCHEMBL8760228 1.00 TYR (0.54) TYRLIPGKDM4EUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344486-A1 PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS CYCLACEL LIMITED (GB) 2015-12-03 US claimed
EP-2610256-A1 Pyrimidine derivatives as protein kinase inhibitors Cyclacel Limited (GB) 2013-07-03 EP claimed
WO-2005061515-A1 VINYLOGOUS 4H-PYRONES AND THEIR USE IN PROMOTING PLANT GROWTH BOTANICAL GARDENS AND PARKS AUTHORITY (AU) 2005-07-07 WO claimed
EP-0077909-B1 HIGH CONSISTENCY-AQUEOUS SLURRY OF POWDERED COAL DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1986-04-09 EP claimed
CN-118103425-A Curable composition, cured product thereof, prepreg, circuit board, build-up film, semiconductor sealing material, and semiconductor device DIC株式会社 2024-05-28 CN disclosed
CN-111886282-B Method for producing pellet and method for producing block 日本瑞翁株式会社 2023-08-22 CN disclosed
WO-2023089998-A1 CURABLE COMPOSITION, CURED PRODUCT THEREOF, PREPREG, CIRCUIT BOARD, BUILD-UP FILM, SEMICONDUCTOR SEALING MATERIAL AND SEMICONDUCTOR DEVICE DIC株式会社 2023-05-25 WO disclosed
CN-109535631-B Block copolymer composition 日本瑞翁株式会社 2023-02-17 CN disclosed
EP-3778718-A1 CRUMBS, PRODUCTION METHOD FOR SAME, AND PRODUCTION METHOD FOR BALE Zeon Corporation (JP) 2021-02-17 EP disclosed
EP-3778720-A1 PRODUCTION METHOD FOR CRUMBS AND PRODUCTION METHOD FOR BALE Zeon Corporation (JP) 2021-02-17 EP disclosed
CN-111886282-A Method for producing pellet and method for producing block 日本瑞翁株式会社 2020-11-03 CN disclosed
WO-2020203811-A1 POLYMER SOLUTION DESOLVATION METHOD 日本ゼオン株式会社 2020-10-08 WO disclosed
US-4213987-A 4-AMINOQUINAZOLINES SANKYO COMPANY LIMITED (JP) 1980-07-22 US disclosed
US-4146726-A HERBICIDES SANKYO COMPANY LIMITED (JP) 1979-03-27 US disclosed
US-4063925-A Herbicidal compositions SANKYO COMPANY LIMITED (JA) 1977-12-20 US disclosed
US-4060402-A HERBICIDE SANKYO COMPANY LIMITED (JA) 1977-11-29 US disclosed
US-4052395-A AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES SANKYO COMPANY LIMITED (JA) 1977-10-04 US disclosed
US-4044018-A Isoxazolone derivatives, their preparation and their use as plant growth regulators SANKYO COMPANY LIMITED (JA) 1977-08-23 US disclosed
US-4036631-A Pyrazolone derivatives and their use as herbicides SANKYO COMPANY LIMITED (JA) 1977-07-19 US disclosed
US-3935731-A Method and means for improving flaw entrapment efficiency in water-washable inspection penetrants ALBURGER JAMES R 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344486-A1 PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS DCK, DTYMK, TK1 TYR 1765/4885LIPG 3368/4885KDM4E 2466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.