Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941089 | 0.82 | KMT2A (0.78) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL173470 | 0.81 | KMT2A (0.75) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL981942 | 0.80 | CTNNB1 (0.48) | KMT2ALMNAMAPTNPC1RAB9A | |
| SCHEMBL29016418 | 0.79 | KMT2A (0.72) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| Iodomethane SCHEMBL10500732 | 0.79 | KMT2A (0.72) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL940699 | 0.79 | KMT2A (0.56) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL28800185 | 0.78 | KMT2A (0.70) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL22624866 | 0.78 | KMT2A (0.82) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL31093167 | 0.78 | KMT2A (0.70) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL31093129 | 0.77 | KMT2A (0.59) | KMT2AL3MBTL1TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299305-B2 | Method for preparing atomoxetine | SCI PHARMTECH, INC. (TW) | 2012-10-30 | — | — | US | disclosed |
| US-8299305-B2 | Method for preparing atomoxetine | SCI PHARMTECH, INC. (TW) | 2012-10-30 | — | — | US | disclosed |
| US-20110319664-A1 | METHOD FOR PREPARING ATOMOXETINE | SCI PHARMTECH, INC. (TW) | 2011-12-29 | — | — | US | disclosed |
| US-20110319664-A1 | METHOD FOR PREPARING ATOMOXETINE | SCI PHARMTECH, INC. (TW) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319664-A1 | METHOD FOR PREPARING ATOMOXETINE | TPH2, HTR1A, HTR2B | KMT2A 361/4885L3MBTL1 4823/4885TDP1 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.