N6-Cyclopentyladenosine

N6-Cyclopentyladenosine

SCHEMBL120481

OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 6/20 1.00
ADORA2A P29274 4/20 1.00
TSHR P16473 3/20 1.00
ADORA2B P29275 3/20 1.00
ADORA1 P30542 3/20 1.00
PMP22 Q01453 2/20 1.00
SLC29A1 Q99808 2/20 1.00
GAA P10253 1/20 1.00
HTT P42858 1/20 1.00
SIGMAR1 Q99720 1/20 1.00
RXFP1 Q9HBX9 1/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
TP53 P04637 1/20 1.00
NFKB1 P19838 1/20 1.00
HIF1A Q16665 1/20 1.00
SMN1; SMN2 Q16637 1/20 0.98
TDP1 Q9NUW8 1/20 0.98
CYP2C19 P33261 1/20 0.98
THPO P40225 1/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N6-Cyclopentyladenosine SCHEMBL12226873 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
N6-Cyclopentyladenosine SCHEMBL7202975 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
N6-Cyclopentyladenosine SCHEMBL8271466 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
N6-Cyclopentyladenosine SCHEMBL381792 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
N6-Cyclopentyladenosine SCHEMBL472508 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
N6-Cyclopentyladenosine SCHEMBL472621 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
N6-Cyclopentyladenosine SCHEMBL12200134 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
N6-Cyclopentyladenosine SCHEMBL20226050 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
N6-Cyclopentyladenosine SCHEMBL18908968 1.00 ADORA3 (1.00) ADORA3ADORA2ATSHRADORA2BADORA1
SCHEMBL12119008 0.99 TSHR (1.00) ADORA3ADORA2ATSHRADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250262274-A1 Designed Biosensors for Enhanced T Cell Therapy ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) 2025-08-21 US claimed
EP-4526335-A1 DESIGNED BIOSENSORS FOR ENHANCED T CELL THERAPY Centre Hospitalier Universitaire Vaudois (CH) 2025-03-26 EP claimed
CN-118845814-A Application of N6-cyclopentyl adenosine, derivatives and salts thereof in treating liver diseases 上海中医药大学 2024-10-29 CN claimed
WO-2024182811-A1 COMPOSITIONS AND METHODS FOR TREATING UTERINE LEIOMYOMAS UNIVERSITY OF SOUTH FLORIDA (US) 2024-09-06 WO claimed
US-20240024243-A1 Fine Dry Particulate Adenosine Compositions and Topical Formulations Including the Same LABORATORY SKIN CARE, INC. 2024-01-25 US claimed
WO-2023222829-A1 DESIGNED BIOSENSORS FOR ENHANCED T CELL THERAPY CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CH) 2023-11-23 WO claimed
CN-114376962-A Drug-loaded nanofiber for acupuncture point thread embedding material and preparation method and application thereof 上海市第四人民医院 2022-04-22 CN claimed
EP-3923962-A2 GENE NETWORKS THAT MEDIATE REMYELINATION OF THE HUMAN BRAIN University of Rochester (US) 2021-12-22 EP claimed
WO-2021003393-A1 METHOD, COMPOSITION, AND APPARATUS FOR TREATING HEADACHE Equinox Ophthalmic, Inc. (US) 2021-01-07 WO claimed
CN-111789950-A Method and pharmaceutical composition for regulating fear memory consolidation 浙江大学 2020-10-20 CN claimed
WO-2009018275-A1 ADENOSINE AND ITS MIMETICS, MODULATORS, TRANSPORT INHIBITORS, AND RECEPTOR AGONISTS AS A THERAPEUTIC TOOL TO REPLACE OR IMPROVE THE EFFICACY OF DEEP BRAIN STIMULATION UNIVERSITY OF ROCHESTER (US) 2009-02-05 WO claimed
US-20070232560-A1 Treatment of skin with adenosine or adenosine analog UNIVERSITY OF MASSACHUSETTS, A MASSACHUSETTS CORPORATION 2007-10-04 US claimed
US-20060240056-A1 Treatment of skin with adenosine or adenosine analog UNIVERSITY OF MASSACHUSETTS, A MASSACHUSETTS CORPORATION 2006-10-26 US claimed
US-20060099568-A1 Signals and molecular species involved in senescence SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2006-05-11 US claimed
JP-2004520404-A 2004-07-08 JP claimed
EP-0996453-B1 METHODS FOR THE INHIBITION OF NEURONAL ACTIVITY BY LOCAL DELIVERY OF ADENOSINE MOHLER HANNS (CH) 2004-04-28 EP claimed
WO-2003104482-A1 SIGNALS AND MOLECULAR SPECIES INVOLVED IN SENESCENCE METABOLIC ENGINEERING LABORATORIES CO., LTD. (KR) 2003-12-18 WO claimed
EP-1363644-A2 MODULATION OF GSK-3BETA ACTIVITY AND ITS DIFFERENT USES Can-Fite Biopharma Ltd. (IL) 2003-11-26 EP claimed
US-6638914-B1 Use in inducing proliferation of the hematopoietic system, in particular, of bone marrow cells, comprising a pharmaceutically acceptable carrier, excipient or diluent and, as an active ingredient, an effective amount of an CAN-FITE BIOPHARMA LTD. (IL) 2003-10-28 US claimed
WO-2002066020-A2 MODULATION OF GSK-3BETA ACTIVITY AND ITS DIFFERENT USES CAN-FITE BIOPHARMA LTD. (IL) 2002-08-29 WO claimed