Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 2/20 | 0.44 |
| ▸ | FDPS | P14324 | 14/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060370 | 0.92 | GGPS1 (0.47) | GGPS1FDPSCHRNA7CHRNA10CHRNA9 | |
| SCHEMBL11952615 | 0.81 | GGPS1 (0.52) | GGPS1FDPS | |
| SCHEMBL12048152 | 0.79 | GGPS1 (0.48) | GGPS1FDPS | |
| SCHEMBL12048259 | 0.78 | GGPS1 (0.52) | GGPS1FDPS | |
| SCHEMBL12048207 | 0.77 | GGPS1 (0.51) | GGPS1FDPS | |
| SCHEMBL12048186 | 0.77 | GGPS1 (0.51) | GGPS1FDPS | |
| SCHEMBL12048200 | 0.77 | GGPS1 (0.51) | GGPS1FDPS | |
| SCHEMBL12048195 | 0.77 | GGPS1 (0.51) | GGPS1FDPS | |
| SCHEMBL12048192 | 0.76 | FDPS (0.40) | GGPS1FDPS | |
| SCHEMBL12048182 | 0.76 | FDPS (0.42) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071573-B2 | Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, A BODY CORPORATE AND POLITIC OF THE STATE OF ILLINOIS (US) | 2011-12-06 | — | — | US | disclosed |
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |