Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 10/20 | 0.42 |
| ▸ | BCHE | P06276 | 9/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060366 | 0.91 | GGPS1 (0.52) | GGPS1ACHEBCHEFDPS | |
| SCHEMBL12436579 | 0.88 | GGPS1 (0.45) | GGPS1ACHEBCHEFDPSMAPT | |
| SCHEMBL12048185 | 0.79 | GGPS1 (0.57) | GGPS1FDPS | |
| SCHEMBL12048194 | 0.79 | GGPS1 (0.44) | GGPS1FDPS | |
| SCHEMBL12048146 | 0.79 | GGPS1 (0.76) | GGPS1FDPS | |
| SCHEMBL11952615 | 0.78 | GGPS1 (0.52) | GGPS1FDPS | |
| SCHEMBL12048259 | 0.78 | GGPS1 (0.52) | GGPS1FDPS | |
| SCHEMBL12048186 | 0.77 | GGPS1 (0.51) | GGPS1FDPS | |
| SCHEMBL12048155 | 0.77 | FDPS (0.49) | GGPS1FDPS | |
| SCHEMBL12048195 | 0.77 | GGPS1 (0.51) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071573-B2 | Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, A BODY CORPORATE AND POLITIC OF THE STATE OF ILLINOIS (US) | 2011-12-06 | — | — | US | disclosed |
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |