SCHEMBL119373

SCHEMBL119373

O=C(C[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)NC(c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.55
TP53 P04637 3/20 0.55
CASP3 P42574 2/20 0.53
KMT2A Q03164 2/20 0.50
TLR2 O60603 2/20 0.48
MDM2 Q00987 5/20 0.48
SLC17A5 Q9NRA2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119621 0.91 MDM2 (0.56) MDM4TP53CASP3KMT2ATLR2
SCHEMBL29561499 0.91 MDM2 (0.56) MDM4TP53CASP3KMT2ATLR2
SCHEMBL120502 0.89 TLR2 (0.57) MDM4TP53CASP3KMT2ATLR2
SCHEMBL16343063 0.87 CASP3 (0.56) MDM4TP53CASP3KMT2ATLR2
SCHEMBL29907908 0.87 CASP3 (0.56) MDM4TP53CASP3KMT2ATLR2
SCHEMBL29907963 0.87 CASP3 (0.56) MDM4TP53CASP3KMT2ATLR2
SCHEMBL16218324 0.87 CASP3 (0.56) MDM4TP53CASP3KMT2ATLR2
SCHEMBL378041 0.87 CASP3 (0.64) MDM4TP53CASP3KMT2AMDM2
SCHEMBL1486199 0.87 CASP3 (0.64) MDM4TP53CASP3KMT2AMDM2
SCHEMBL29352428 0.87 CASP3 (0.64) MDM4TP53CASP3KMT2AMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed