SCHEMBL120505

SCHEMBL120505

CC(=O)NCSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC17A5 Q9NRA2 1/20 0.54
MDM4 O15151 3/20 0.52
TP53 P04637 3/20 0.52
TLR2 O60603 2/20 0.51
CASP3 P42574 2/20 0.49
MDM2 Q00987 3/20 0.47
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400856 1.00 SLC17A5 (0.54) SLC17A5MDM4TP53TLR2CASP3
SCHEMBL29374576 1.00 SLC17A5 (0.54) SLC17A5MDM4TP53TLR2CASP3
SCHEMBL25320019 1.00 SLC17A5 (0.54) SLC17A5MDM4TP53TLR2CASP3
SCHEMBL30665728 0.91 MDM4 (0.51) SLC17A5MDM4TP53TLR2CASP3
SCHEMBL29202254 0.90 TLR2 (0.50) SLC17A5MDM4TP53TLR2CASP3
SCHEMBL5311930 0.87 MDM2 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL29401557 0.87 SLC17A5 (0.43) SLC17A5MDM4TP53TLR2CASP3
SCHEMBL5311923 0.87 MDM2 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL27699497 0.87 SLC17A5 (0.43) SLC17A5MDM4TP53TLR2CASP3
SCHEMBL29398108 0.87 SLC17A5 (0.58) SLC17A5MDM4TP53TLR2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113788877-B Novel insect kinin analogues and application thereof in aphid control 中国农业大学 2023-11-21 CN disclosed
WO-2022111713-A9 POLYPEPTIDE CONTAINING DISULFIDE BONDS AND CAPABLE OF INHIBITING ACTIVITY OF SERINE PROTEASE, DERIVED HYBRID PEPTIDE THEREOF, AND USE THEREOF 中国医学科学院药物研究所 2023-07-27 WO disclosed
CN-114573686-A Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof 中国医学科学院药物研究所 2022-06-03 CN disclosed
CN-113788877-A Novel insect kinin analogs and application thereof in aphid control 中国农业大学 2021-12-14 CN disclosed
US-8969289-B2 Serum albumin binding molecules BRISTOL-MYERS SQUIBB COMPANY (US) 2015-03-03 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20110305663-A1 SERUM ALBUMIN BINDING MOLECULES BRISTOL-MYERS SQUIBB COMPANY (US) 2011-12-15 US disclosed
US-6310040-B1 FOR PROMOTING THE SURVIVAL OF PHOTORECEPTORS IN A MAMMAL CEPHALON, INC. 2001-10-30 US disclosed
US-5776897-A Treating disorders by application of insulin-like growth factors and analogs CEPHALON, INC. (US) 1998-07-07 US disclosed
US-5703045-A NERVOUS SYSTEM DISORDERS CEPHALON, INC. (US) 1997-12-30 US disclosed
US-5652214-A ENHANCING SURVIVAL OF NEURONAL CELLS IN HEAD AND SPINAL CORD AFTER INJURY, ALSO TREATMENT OF AGING, ALZHEIMER*S, STROKE, EPILEPSY CEPHALON, INC. (US) 1997-07-29 US disclosed
EP-0604605-A4 TREATING DISORDERS BY APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS. CEPHALON INC (US) 1997-01-29 EP disclosed
EP-0670729-A1 TREATING RETINAL NEURONAL DISORDERS BY THE APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS CEPHALON, INC. (US) 1995-09-13 EP disclosed
EP-0670729-A4 TREATING RETINAL NEURONAL DISORDERS BY THE APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS. CEPHALON INC (US) 1995-05-10 EP disclosed
EP-0604605-A1 TREATING DISORDERS BY APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS CEPHALON, INC. (US) 1994-07-06 EP disclosed
WO-1993020836-A1 TREATING DISORDERS BY APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS CEPHALON, INC. (US) 1993-10-28 WO disclosed
WO-1993008826-A1 TREATING RETINAL NEURONAL DISORDERS BY THE APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS CEPHALON, INC. (US) 1993-05-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110305663-A1 SERUM ALBUMIN BINDING MOLECULES FN1, ALB, FABP3 SLC17A5 417/4885MDM4 3498/4885TP53 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.