SCHEMBL29398108

SCHEMBL29398108

CCSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC17A5 Q9NRA2 1/20 0.58
MDM4 O15151 3/20 0.55
TP53 P04637 3/20 0.55
CASP3 P42574 2/20 0.53
TLR2 O60603 2/20 0.52
MDM2 Q00987 3/20 0.49
TNF P01375 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1486194 1.00 SLC17A5 (0.58) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL19888241 0.89 SLC17A5 (0.58) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL3436129 0.89 MDM4 (0.58) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL29400770 0.89 MDM4 (0.58) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL1001473 0.89 MDM4 (0.58) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL15788337 0.89 SLC17A5 (0.54) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL4719374 0.89 TLR2 (0.56) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL15788342 0.89 SLC17A5 (0.54) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL3218391 0.89 MDM4 (0.53) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL31398319 0.89 MDM4 (0.53) SLC17A5MDM4TP53CASP3TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12427210-B2 Compounds comprising a fibroblast activation protein ligand and use thereof 3B PHARMACEUTICALS GMBH (DE) 2025-09-30 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
US-20220273831-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2022-09-01 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273831-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF FIBP, FGF2, FRS2 SLC17A5 1272/4885MDM4 1219/4885TP53 595/4885
US-12427210-B2 Compounds comprising a fibroblast activation protein ligand and use thereof FIBP, FGF2, FRS2 SLC17A5 1272/4885MDM4 1219/4885TP53 595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.