Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12052948 | 0.94 | PRMT1 (0.37) | PRMT1ENPP2PHLPP2KDM4EMEN1 | |
| SCHEMBL12052535 | 0.92 | ENPP2 (0.32) | ENPP2PHLPP2THRB | |
| SCHEMBL12052809 | 0.89 | ENPP2 (0.36) | ENPP2PHLPP2MEN1MAPTKMT2A | |
| SCHEMBL12052533 | 0.88 | THRB (0.37) | ENPP2PHLPP2MEN1MAPTKMT2A | |
| SCHEMBL12052532 | 0.88 | THRB (0.37) | ENPP2PHLPP2MEN1MAPTKMT2A | |
| SCHEMBL13340934 | 0.88 | PRMT1 (0.36) | PRMT1ENPP2PHLPP2KDM4EMEN1 | |
| SCHEMBL12052821 | 0.87 | ENPP2 (0.33) | ENPP2PHLPP2KDM4EMEN1MAPT | |
| SCHEMBL12052860 | 0.87 | PHLPP2 (0.41) | ENPP2PHLPP2KDM4EMEN1MAPT | |
| SCHEMBL13996418 | 0.86 | ENPP2 (0.33) | ENPP2PHLPP2THRB | |
| SCHEMBL12053113 | 0.86 | PRMT1 (0.36) | PRMT1ENPP2KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080101-B2 | Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20080295732-A1 | Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use | DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) | 2008-12-04 | — | — | US | disclosed |