Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12053161 | 0.93 | ENPP2 (0.47) | ENPP2CA2CA3AMY1ATHRB | |
| SCHEMBL12053238 | 0.90 | ENPP2 (0.44) | ENPP2CA2CA3AMY1ATHRB | |
| SCHEMBL12053245 | 0.90 | THRB (0.38) | ENPP2THRBMAPTKDM4EALDH1A1 | |
| SCHEMBL12053216 | 0.90 | ENPP2 (0.45) | ENPP2CA2CA3AMY1ATHRB | |
| SCHEMBL12053167 | 0.90 | ENPP2 (0.45) | ENPP2CA2CA3AMY1ATHRB | |
| SCHEMBL12053021 | 0.89 | ENPP2 (0.46) | ENPP2CA2CA3AMY1ATHRB | |
| SCHEMBL12052871 | 0.87 | THRB (0.38) | ENPP2THRBMAPTKDM4EALDH1A1 | |
| SCHEMBL12053136 | 0.87 | ENPP2 (0.44) | ENPP2CA2CA3AMY1ATHRB | |
| SCHEMBL12053397 | 0.86 | ENPP2 (0.44) | ENPP2CA2CA3AMY1ATHRB | |
| SCHEMBL12053241 | 0.86 | ENPP1 (0.35) | ENPP2THRBMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080101-B2 | Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20080295732-A1 | Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use | DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) | 2008-12-04 | — | — | US | disclosed |