SCHEMBL12053335

SCHEMBL12053335

COc1ccc(/N=N/c2c(SOOO)cc3cc(Nc4nc(F)nc(F)c4Cl)ccc3c2O)c(S(=O)(=O)O)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 3/20 0.42
▸ CARM1 Q86X55 1/20 0.42
▸ CD40 P25942 1/20 0.38
▸ CD40LG P29965 1/20 0.38
▸ ENPP2 Q13822 9/20 0.36
▸ PHLPP2 Q6ZVD8 1/20 0.34
▸ PTPN11 Q06124 1/20 0.32
▸ PRMT3 O60678 1/20 0.32
▸ EP300 Q09472 1/20 0.32
▸ PRMT6 Q96LA8 1/20 0.32
▸ MPL P40238 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HIF1A Q16665 1/20 0.31
▸ FUT8 Q9BYC5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13599536 0.91 ENPP2 (0.40) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL18832710 0.90 PRMT1 (0.49) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL14388853 0.90 PRMT1 (0.49) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL13088669 0.84 ENPP2 (0.49) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL12053343 0.83 CD40 (0.32) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL13088675 0.82 ENPP2 (0.48) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL29462936 0.82 PRMT1 (0.60) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL15544626 0.82 PRMT1 (0.60) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL15544630 0.82 PRMT1 (0.60) PRMT1CARM1CD40CD40LGENPP2
SCHEMBL11911523 0.82 ENPP2 (0.55) PRMT1CARM1CD40CD40LGENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8080101-B2 Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-12-20 — — US disclosed
US-7708786-B2 Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2010-05-04 — — US disclosed
US-20090025152-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2009-01-29 — — US disclosed
US-20080295732-A1 Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) 2008-12-04 — — US disclosed
US-7455699-B2 Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-11-25 — — US disclosed
US-20070271711-A1 Dye Mixtures of Fibre-Reactive Azo Dyes Production and Use Thereof DYSTAR TEXTILFARBEN GMBH & CO., DEUTSCHLAND KG (DE) 2007-11-29 — — US disclosed
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