SCHEMBL11911523

SCHEMBL11911523

COc1ccc(N=Nc2cc(C)c(N=Nc3cc(C)c(N=Nc4c(SOOO)cc5cc(Nc6ccccc6)ccc5c4O)cc3C)cc2C)c(S(=O)(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 10/20 0.55
▸ CD40 P25942 1/20 0.39
▸ CD40LG P29965 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ PHLPP2 Q6ZVD8 2/20 0.39
▸ PRMT1 Q99873 2/20 0.38
▸ CARM1 Q86X55 1/20 0.38
▸ PRMT3 O60678 1/20 0.38
▸ EP300 Q09472 1/20 0.38
▸ PRMT6 Q96LA8 1/20 0.38
▸ MEN1 O00255 1/20 0.36
▸ THRB P10828 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ MPL P40238 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14001679 0.96 ENPP2 (0.60) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL13088669 0.96 ENPP2 (0.49) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL14001677 0.96 ENPP2 (0.51) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL13088675 0.95 ENPP2 (0.48) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL13088672 0.93 ENPP2 (0.55) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL13088668 0.93 ENPP2 (0.55) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL14001678 0.92 ENPP2 (0.53) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL14001674 0.91 ENPP2 (0.45) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL13088708 0.91 ENPP2 (0.52) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL14001676 0.91 ENPP2 (0.53) ENPP2CD40CD40LGALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8232375-B2 Azo compound, and dye-containing polarizing film comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-07-31 — — US disclosed
US-20100226008-A1 Azo Compound, And Dye-Containing Polarizing Film Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-09-09 — — US disclosed
US-7445822-B2 Azo compounds and dye-type polarizing films or plates containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-04 — — US disclosed
US-20080094549-A1 Azo Compounds And Dye-Type Polarizing Films Or Plates Containing The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-04-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080094549-A1 Azo Compounds And Dye-Type Polarizing Films Or Plates Containing The Same CRY1, SCO2, SPR ENPP2 1986/4885CD40 3865/4885CD40LG 4237/4885
US-20100226008-A1 Azo Compound, And Dye-Containing Polarizing Film Comprising The Same RCC1, IK, NAP1L1 ENPP2 3872/4885CD40 4552/4885CD40LG 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback