Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | DRD4 | P21917 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12033410 | 0.86 | HTR2A (0.66) | HTR2AHTR2CHTR2BDRD4ALDH1A1 | |
| SCHEMBL27619102 | 0.86 | HTR2A (0.70) | HTR2AHTR2CHTR2BDRD4ALDH1A1 | |
| SCHEMBL1482123 | 0.86 | HTR2A (0.69) | HTR2AHTR2CHTR2BDRD4ALDH1A1 | |
| SCHEMBL1066467 | 0.85 | HTR2A (0.72) | HTR2AHTR2CHTR2BDRD4ALDH1A1 | |
| Bromide SCHEMBL14053867 | 0.85 | HTR2A (0.64) | HTR2AHTR2CHTR2BDRD4ALDH1A1 | |
| SCHEMBL7459360 | 0.84 | HTR2A (0.71) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| Hydrochloric Acid SCHEMBL4653252 | 0.84 | HTR2A (0.71) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| SCHEMBL2744427 | 0.83 | HTR2A (0.69) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| Hydrochloric Acid SCHEMBL9742137 | 0.82 | HTR2A (0.67) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| Hydrochloric Acid SCHEMBL6684157 | 0.82 | HTR2A (0.60) | HTR2AHTR2CHTR2BDRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110312996-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312996-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, PYGL | HTR2A 4473/4885HTR2C 4199/4885HTR2B 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.