Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | HTR2B | P41595 | 1/20 | 0.71 |
| ▸ | DRD4 | P21917 | 3/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066467 | 0.89 | HTR2A (0.72) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| Hydrochloric Acid SCHEMBL4653252 | 0.88 | HTR2A (0.71) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| SCHEMBL1482123 | 0.87 | HTR2A (0.69) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| SCHEMBL2744427 | 0.87 | HTR2A (0.69) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| Hydrochloric Acid SCHEMBL9742137 | 0.85 | HTR2A (0.67) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| SCHEMBL9407904 | 0.84 | HDAC4 (0.72) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| SCHEMBL12341280 | 0.84 | HDAC1 (0.81) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| SCHEMBL12033410 | 0.84 | HTR2A (0.66) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| SCHEMBL27619102 | 0.84 | HTR2A (0.70) | HTR2AHTR2CHTR2BDRD4HDAC4 | |
| SCHEMBL12053542 | 0.84 | HTR2A (0.66) | HTR2AHTR2CHTR2BDRD4HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |