Aspartic Acid

Aspartic Acid

SCHEMBL120544

N[C@@H](CC(=O)O)C(=O)[O-].N[C@@H](CC(=O)O)C(=O)[O-].[Ca+2]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5

The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.39
GABRR1 P24046 2/20 0.39
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
GRIK1 P39086 2/20 0.37
GRIK2 Q13002 2/20 0.37
GRM1 Q13255 2/20 0.37
GRM2 Q14416 2/20 0.37
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GSR P00390 1/20 0.37
CYP1A2 P05177 1/20 0.37
GRM5 P41594 1/20 0.37
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37
GRIA3 P42263 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aspartic Acid SCHEMBL10601207 0.97 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL17747944 0.97 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL4019503 0.97 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL3976768 0.97 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL1987594 0.97 SLC22A6 (0.41) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL50775 0.95 SLC22A6 (0.39) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL16431399 0.95 SLC22A6 (0.39) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL5247248 0.95 SLC22A6 (0.39) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL14343482 0.95 SLC22A6 (0.39) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL518279 0.95 SLC22A6 (0.39) SLC22A6GABRR1LMNATDP1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122056387-A Composition for promoting joint health and preparation method and application thereof 吉林衡美宇创健康科技有限公司 2026-05-19 CN claimed
CN-122056386-A Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-19 CN claimed
CN-122030612-A Shear-resistant slow-release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-15 CN claimed
US-12582149-B1 Functional additive for hot beverages and foods MILJKOVIC IGOR (US) 2026-03-24 US claimed
US-20260081133-A1 ZINC ELECTRODE FOR ALKALINE NICKEL-ZINC BATTERY AND PREPARATION METHOD THEREFOR DONGGUAN CHAO BA BATTERIES CO LTD SHENZHEN INNOVATION CENTER (CN) 2026-03-19 US claimed
EP-4627938-A1 COMPOSITION FOR RESISTING ENTERITIS AND/OR PROTECTING INTEGRITY OF INTESTINAL BARRIER, AND USE THEREOF Inner Mongolia Yili Industrial Group Co. Ltd. (CN) 2025-10-08 EP claimed
EP-4298923-B1 METHOD FOR PREVENTING CAKING OF XYLITOL AND CALCIUM ASPARTATE MIXTURE ZHEJIANG HUAKANG PHARMACEUTICAL CO LTD (CN) 2025-06-18 EP claimed
CN-119970605-A Whitening toothpaste capable of preventing caries and inhibiting dental plaque and preparation method thereof 广州虹云峰科技有限责任公司 2025-05-13 CN claimed
CN-119924527-A Composition for promoting bone health and bone formation, application and product thereof 合生元(长沙)营养食品有限公司 2025-05-06 CN claimed
CN-119769737-A Gamma-aminobutyric acid product and preparation method thereof 江西维莱营健高科有限公司 2025-04-08 CN claimed
WO-1999026491-A1 FORTIFIED CONFECTIONERY DELIVERY SYSTEMS AND METHODS OF PREPARATION THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 1999-06-03 WO claimed
EP-0909992-A1 Water-soluble photoresist composition Fuji Chemicals Industrial Co., Ltd. (JP) 1999-04-21 EP claimed
EP-0770057-A1 METHOD FOR PRODUCING CALCIUM SALTS OF [S,S]-ETHYLENEDIAMINE-N,N'-DISUCCINIC ACID ALBEMARLE CORPORATION (US) 1997-05-02 EP claimed
US-5550285-A Method for producing calcium salts of [S,S]-ethylenediamine-N,N'-disuccinic acid ALBEMARLE CORPORATION 1996-08-27 US claimed
WO-1996001804-A1 METHOD FOR PRODUCING CALCIUM SALTS OF [S,S]-ETHYLENEDIAMINE-N,N'-DISUCCINIC ACID ALBEMARLE CORPORATION (US) 1996-01-25 WO claimed
US-4738856-A Beverage and method for making a beverage for the nutritional supplementation of calcium in humans NUTRITION TECHNOLOGIES, INC. (US) 1988-04-19 US claimed
EP-0246177-A2 A beverage and method for making a beverage for the nutritional supplementation of calcium in humans Clark, George H. (US) 1987-11-19 EP claimed
US-4479840-A SYNTHETIC RESIN EMULSION AND GELLING AGENT; ORGANIC AND INORGANIC SALTS SUNSTAR GIKEN KABUSHIKI (JP) 1984-10-30 US claimed
US-4386992-A Two-part adhesive and bonding method employing same SUNSTAR CHEMICAL IND. CO., LTD. (JP) 1983-06-07 US claimed
US-4288619-A AS CALCIUM SALTS, ION EXCHANGE RESIN ROQUETTE FRERES (FR) 1981-09-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260081133-A1 ZINC ELECTRODE FOR ALKALINE NICKEL-ZINC BATTERY AND PREPARATION METHOD THEREFOR SLC39A11, SLC30A7, SLC39A7 SLC22A6 1508/4885GABRR1 535/4885LMNA 2911/4885
US-12582149-B1 Functional additive for hot beverages and foods SOD1, KCNN1, KCNN3 SLC22A6 1697/4885GABRR1 1403/4885LMNA 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.