Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064224 | 0.94 | TYMP (0.34) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL14064222 | 0.87 | TYMP (0.31) | TYMP | |
| SCHEMBL12765859 | 0.87 | TYMP (0.32) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL13374809 | 0.87 | TYMP (0.32) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL13329991 | 0.87 | TYMP (0.32) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL12056704 | 0.86 | NQO2 (0.32) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL24829632 | 0.78 | TYMP (0.32) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL25747161 | 0.78 | TYMP (0.32) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL14005196 | 0.77 | TYMP (0.31) | TYMP | |
| SCHEMBL21901427 | 0.76 | RNASE1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084589-B2 | Phosphoramidite nucleoside analogs | UNIVERSITY OF MASSACHUSETTS (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090136940-A1 | PHOSPHORAMIDITE NUCLEOSIDE ANALOGS | UNIVERSITY OF MASSACHUSETTS (US) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136940-A1 | PHOSPHORAMIDITE NUCLEOSIDE ANALOGS | TYMP, PNP, TYMS | TYMP 1/4885KIF11 3368/4885KCNH2 4858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.