Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.40 |
| ▸ | TK2 | O00142 | 5/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24299731 | 0.95 | RNASE1 (0.42) | RNASE1TK2TYMSTK1 | |
| SCHEMBL13213625 | 0.93 | RNASE1 (0.42) | RNASE1TK2TYMSTK1 | |
| SCHEMBL21901667 | 0.92 | RNASE1 (0.41) | RNASE1TK2TYMSTK1 | |
| SCHEMBL6324532 | 0.91 | RNASE1 (0.45) | RNASE1TK2TYMSTK1 | |
| SCHEMBL21901663 | 0.91 | RNASE1 (0.40) | RNASE1TK2TK1 | |
| SCHEMBL21901419 | 0.90 | RNASE1 (0.40) | RNASE1TK2TYMSTK1 | |
| SCHEMBL24115407 | 0.90 | RNASE1 (0.40) | RNASE1TK2TYMSTK1 | |
| SCHEMBL22984007 | 0.90 | RNASE1 (0.40) | RNASE1TK2TYMSTK1 | |
| SCHEMBL22872065 | 0.90 | RNASE1 (0.40) | RNASE1TK2TYMSTK1 | |
| SCHEMBL13901245 | 0.90 | RNASE1 (0.40) | RNASE1TK2TYMSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096649-A1 | IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE | HORIZON TECHNOLOGY FINANCE CORPORATION | 2022-03-31 | — | — | US | disclosed |
| US-20220056069-A1 | IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE | HORIZON TECHNOLOGY FINANCE CORPORATION | 2022-02-24 | — | — | US | disclosed |
| US-11203611-B2 | Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use | TOLLNINE, INC. (US) | 2021-12-21 | — | — | US | disclosed |
| WO-2020081744-A1 | IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE | TOLLNINE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220056069-A1 | IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE | TYMP, DUT, PAICS | RNASE1 127/4885TK2 331/4885TYMS 4/4885 |
| US-11203611-B2 | Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use | TYMP, DUT, PAICS | RNASE1 127/4885TK2 331/4885TYMS 4/4885 |
| US-20220096649-A1 | IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE | PBK, CD47, NCL | RNASE1 89/4885TK2 73/4885TYMS 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.