Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954884 | 0.85 | ELANE (0.41) | ELANERAB9ASMN1; SMN2SIGMAR1OPRM1 | |
| SCHEMBL3026097 | 0.76 | ELANE (0.44) | ELANERAB9ASMN1; SMN2SIGMAR1OPRM1 | |
| SCHEMBL4954393 | 0.69 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7067422 | 0.69 | ELANE (0.42) | ELANERAB9ASMN1; SMN2SIGMAR1OPRM1 | |
| SCHEMBL13249587 | 0.68 | ELANE (0.41) | ELANERAB9ASMN1; SMN2SIGMAR1OPRM1 | |
| SCHEMBL7073839 | 0.66 | ELANE (0.36) | ELANERAB9ASMN1; SMN2SIGMAR1OPRM1 | |
| SCHEMBL7070549 | 0.66 | ELANE (0.44) | ELANEOPRM1MEN1KMT2AGAA | |
| SCHEMBL6228586 | 0.65 | ELANE (0.46) | ELANEALDH1A1KMT2ALMNAGAA | |
| SCHEMBL9578136 | 0.64 | RAB9A (0.47) | ELANERAB9ASMN1; SMN2SIGMAR1OPRM1 | |
| SCHEMBL22054795 | 0.63 | TMEM97 (0.45) | RAB9ASMN1; SMN2SIGMAR1OPRM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319535-A1 | IN-CAN STABILIZERS | NESVADBA PETER (CH) | 2011-12-29 | — | — | US | disclosed |