Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951419 | 0.86 | ITGB3 (0.67) | LPAR3LPAR1ENPP2ITGB3ITGA2B | |
| SCHEMBL19683081 | 0.84 | ACACB (0.65) | ACACB | |
| SCHEMBL21337036 | 0.81 | CNR1 (0.60) | ACACB | |
| SCHEMBL24916583 | 0.81 | ACACB (0.61) | ACACBITGB3ITGA2B | |
| SCHEMBL14295054 | 0.79 | SMN1; SMN2 (0.61) | ACACB | |
| SCHEMBL19683053 | 0.77 | ACACB (0.56) | ACACBITGB3ITGA2B | |
| SCHEMBL8426579 | 0.76 | SMN1; SMN2 (0.55) | ACACB | |
| SCHEMBL23442092 | 0.76 | EPHX2 (0.59) | ACACB | |
| SCHEMBL12001310 | 0.76 | ACACB (0.82) | ACACB | |
| SCHEMBL7211418 | 0.76 | FAAH (0.59) | LPAR3LPAR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319362-A1 | STAT3 LIGANDS AND THERAPEUTIC USES THEREOF | WANG SHAOMENG (US) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319362-A1 | STAT3 LIGANDS AND THERAPEUTIC USES THEREOF | STAT3, JAK2, STAT6 | ACACB 3019/4885LPAR3 2359/4885LPAR1 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.