Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24133452 | 0.98 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL26192818 | 0.98 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL26750525 | 0.98 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL25971770 | 0.98 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL7796308 | 0.92 | — | — | |
| SCHEMBL21251603 | 0.83 | CASP2 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL23394747 | 0.83 | CASP2 (0.48) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL8986277 | 0.83 | CASP2 (0.48) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL19936681 | 0.82 | FAAH (0.41) | EPHX1ZDHHC20ZDHHC2CASP2FAAH | |
| SCHEMBL7790036 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219594-A1 | Benzimidazole-imidazole Derivatives | JANSSEN SCIENCES IRELAND UC (IE) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219594-A1 | Benzimidazole-imidazole Derivatives | HAVCR2, CBR3, ZC3HAV1 | EPHX1 4249/4885ZDHHC20 3086/4885ZDHHC2 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.