Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.34 |
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069596 | 0.94 | CA1 (0.39) | SPHK1SPHK2EPHX1CES2CES1 | |
| Hydrochloric Acid SCHEMBL10755387 | 0.92 | GRIN2D (0.40) | SPHK1SPHK2EPHX1CES2CES1 | |
| SCHEMBL27443919 | 0.84 | SPHK1 (0.42) | SPHK1SPHK2EPHX1CES2CES1 | |
| SCHEMBL27971354 | 0.82 | SPHK2 (0.44) | SPHK1SPHK2DNM1NOS3NOS1 | |
| SCHEMBL20285412 | 0.80 | CA1 (0.44) | EPHX1CES2CES1MEN1FAAH | |
| SCHEMBL7612423 | 0.79 | GPR84 (0.41) | EPHX1DNM1MEN1FAAHTP53 | |
| SCHEMBL11238758 | 0.79 | GPR84 (0.41) | EPHX1DNM1MEN1FAAHTP53 | |
| SCHEMBL11226764 | 0.79 | GPR84 (0.41) | EPHX1DNM1MEN1FAAHTP53 | |
| SCHEMBL10340400 | 0.79 | CA12 (0.41) | SPHK1SPHK2DNM1NOS3NOS1 | |
| SCHEMBL2183312 | 0.79 | GPR84 (0.41) | EPHX1DNM1MEN1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539099-A4 | REVERSED LIQUID CRYSTALLINE PHASES WITH NON-PARAFFIN HYDROPHOBES | LYOTROPIC THERAPEUTICS LLC (US) | 2009-03-18 | — | — | EP | claimed |
| EP-1539099-A2 | REVERSED LIQUID CRYSTALLINE PHASES WITH NON-PARAFFIN HYDROPHOBES | Lyotropic Therapeutics, LLC (US) | 2005-06-15 | — | — | EP | claimed |
| US-20040022820-A1 | Reversed liquid crystalline phases with non-paraffin hydrophobes | LYOTROPIC THERAPEUTICS, INC. | 2004-02-05 | — | — | US | claimed |
| WO-2003106382-A2 | REVERSED LIQUID CRYSTALLINE PHASES WITH NON-PARAFFIN HYDROPHOBES | LYOTROPIC THERAPEUTICS, INC. (US) | 2003-12-24 | — | — | WO | claimed |
| US-20020102280-A1 | Solvent systems for pharmaceutical agents | LYOTROPIC THERAPEUTICS, INC. | 2002-08-01 | — | — | US | claimed |
| US-8728829-B2 | Compositions for binding to assay substrata and methods of using | LYOTROPIC THERAPEUTICS, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20110027813-A1 | Compositions for Binding to Assay Substrata and Methods of Using | ANDERSON DAVID M | 2011-02-03 | — | — | US | disclosed |
| US-7838307-B2 | Compositions for binding to assay substrata and methods of using | LYOTROPIC THERAPEUTICS, INC. (US) | 2010-11-23 | — | — | US | disclosed |
| EP-2142927-A1 | A NANOPOROUS PARTICLE WITH A RETAINED TARGET | Lyotropic Therapeutics, Inc. (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20090297493-A1 | NANOPOROUS PARTICLE WITH A RETAINED TARGET | ANDERSON DAVID | 2009-12-03 | — | — | US | disclosed |
| EP-1539099-A4 | REVERSED LIQUID CRYSTALLINE PHASES WITH NON-PARAFFIN HYDROPHOBES | LYOTROPIC THERAPEUTICS LLC (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-1408932-A4 | PARTICLES WITH IMPROVED SOLUBILIZATION CAPACITY | LYOTROPIC THERAPEUTICS INC (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2003000236-A1 | PARTICLES WITH IMPROVED SOLUBILIZATION CAPACITY | LYOTROPIC THERAPEUTICS, INC (US) | 2003-01-03 | — | — | WO | disclosed |
| US-6482517-B1 | Coated particles, methods of making and using | SELECT RELEASE, L.C. | 2002-11-19 | — | — | US | disclosed |
| US-20020102280-A1 | Solvent systems for pharmaceutical agents | LYOTROPIC THERAPEUTICS, INC. | 2002-08-01 | — | — | US | disclosed |
| WO-2002043696-A1 | SOLVENT SYSTEMS FOR PHARMACEUTICAL AGENTS | LYOTROPIC THERAPEUTICS, INC. (US) | 2002-06-06 | — | — | WO | disclosed |
| CN-1248177-A | Coated particles, method of making and using | SELECT RELEASE L C (US) | 2000-03-22 | — | — | CN | disclosed |
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4338441-A | CYCLIZATION OF AMIDINOUREA OR AMIDINOTHIOUREA WITH ACTIVE METHYLIDENE COMPOUND | WILLIAM H. RORER, INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4246409-A | ANTIDIARRHEAL AGENTS | WILLIAM H. RORER, INC. (US) | 1981-01-20 | — | — | US | disclosed |