Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522270 | 0.80 | MAPT (0.54) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL19286172 | 0.79 | ALDH1A1 (0.47) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL11072641 | 0.76 | KMT2A (0.73) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4125057 | 0.75 | ALDH1A1 (0.47) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL11067801 | 0.68 | NPC1 (0.62) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL6819240 | 0.68 | ALDH1A1 (0.49) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5081276 | 0.67 | NOX1 (0.85) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL8956349 | 0.67 | NOX1 (0.85) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL8956455 | 0.67 | MAPT (0.75) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5445907 | 0.67 | MAPT (0.75) | GAAKMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084641-B2 | Organocataslysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-12-27 | — | — | US | disclosed |