Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391669 | 0.93 | MAOA (0.48) | MAOAMAOBSIGMAR1SLC18A3KDM4E | |
| SCHEMBL17383970 | 0.93 | MAOA (0.48) | MAOAMAOBSIGMAR1SLC18A3KDM4E | |
| SCHEMBL12935341 | 0.87 | MAOA (0.45) | MAOAMAOBSIGMAR1KDM4E | |
| SCHEMBL11937070 | 0.84 | SIGMAR1 (0.57) | SIGMAR1HTR2AHTR2CHTR2BSLC18A3 | |
| Hydrochloric Acid SCHEMBL3774275 | 0.83 | KDM4E (0.40) | MAOAMAOBSIGMAR1HTR2AHTR2C | |
| SCHEMBL18221709 | 0.83 | SIGMAR1 (0.67) | SIGMAR1HTR2AHTR2CHTR2BOPRM1 | |
| SCHEMBL8472418 | 0.82 | SIGMAR1 (0.45) | SIGMAR1HTR2AHTR2CHTR2BEBP | |
| SCHEMBL11937071 | 0.81 | SIGMAR1 (0.59) | SIGMAR1HTR2AHTR2CHTR2BEBP | |
| SCHEMBL12935318 | 0.81 | MAOA (0.40) | MAOAMAOBHTR2AHTR2C | |
| SCHEMBL29391452 | 0.81 | MAOA (0.40) | MAOAMAOBSIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148962-A1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF | 大正製薬株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |