Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986571 | 0.86 | VCAM1 (0.51) | VCAM1LMNAMAPTALDH3A1ALDH1A1 | |
| SCHEMBL9980480 | 0.85 | VCAM1 (0.52) | VCAM1LMNAMAPTALDH3A1ALDH1A1 | |
| SCHEMBL12065554 | 0.83 | SCN9A (0.41) | LMNASCN9ACA1CA2L3MBTL1 | |
| SCHEMBL12067872 | 0.77 | VCAM1 (0.57) | VCAM1LMNAMAPTALDH3A1ALDH1A1 | |
| SCHEMBL12067909 | 0.76 | MAPT (0.70) | VCAM1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31009412 | 0.74 | TUBB4A (0.42) | LMNAMAPTALDH1A1PTPN1POLB | |
| SCHEMBL31009396 | 0.74 | TUBB4A (0.42) | LMNAMAPTALDH1A1PTPN1POLB | |
| SCHEMBL29149508 | 0.74 | TUBB4A (0.42) | LMNAMAPTALDH1A1PTPN1POLB | |
| SCHEMBL6001772 | 0.74 | PTPN1 (0.58) | LMNAMAPTALDH3A1ALDH1A1EPAS1 | |
| SCHEMBL2278928 | 0.74 | VCAM1 (0.53) | VCAM1LMNAMAPTALDH3A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |