Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 19/20 | 0.77 |
| ▸ | BRAF | P15056 | 12/20 | 0.77 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065587 | 0.87 | TNNI3K (0.78) | TNNI3KBRAF | |
| SCHEMBL12065586 | 0.87 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL12067164 | 0.84 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL12065588 | 0.82 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL9985710 | 0.77 | TNNI3K (0.47) | TNNI3KBRAF | |
| SCHEMBL12066386 | 0.74 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL6883908 | 0.73 | TNNI3K (0.72) | TNNI3KBRAF | |
| SCHEMBL12065583 | 0.73 | BRAF (0.60) | TNNI3KBRAFKIT | |
| SCHEMBL12067158 | 0.72 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL12067153 | 0.71 | TNNI3K (1.00) | TNNI3KBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |