Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 13/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066026 | 0.89 | PDE2A (0.37) | PDE2ASCN10ASCN1AKCNH2SCN5A | |
| SCHEMBL14763244 | 0.88 | PDE2A (0.36) | PDE2ASCN10ASCN1AKCNH2SCN5A | |
| SCHEMBL12065286 | 0.88 | SCN10A (0.38) | PDE2ASCN10A | |
| SCHEMBL12066007 | 0.83 | SCN10A (0.40) | PDE2ASCN10A | |
| SCHEMBL12065653 | 0.82 | TOP2A (0.39) | PDE2ASCN10A | |
| SCHEMBL12065287 | 0.80 | SCN10A (0.36) | PDE2ASCN10A | |
| SCHEMBL12066025 | 0.78 | SCN10A (0.45) | PDE2ASCN10A | |
| SCHEMBL12066012 | 0.78 | MEN1 (0.45) | PDE2ASCN10A | |
| SCHEMBL14763552 | 0.77 | SCN10A (0.43) | PDE2ASCN10A | |
| SCHEMBL12065657 | 0.76 | MLKL (0.51) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148956-A1 | FUSED IMIDAZOLE DERIVATIVE | トーアエイヨー株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |