Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | CBFB | Q13951 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066025 | 0.89 | SCN10A (0.45) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL12065255 | 0.88 | SCN10A (0.40) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL14762773 | 0.86 | SCN10A (0.43) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL12066550 | 0.86 | MLKL (0.43) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL12066012 | 0.86 | MEN1 (0.45) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL14762946 | 0.85 | TRPV1 (0.40) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL12066007 | 0.85 | SCN10A (0.40) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL12065647 | 0.85 | SCN10A (0.40) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL12066029 | 0.85 | SCN10A (0.40) | SCN10AMEN1HTTKMT2ATRPV1 | |
| SCHEMBL12065657 | 0.84 | MLKL (0.51) | SCN10AMEN1KMT2AALDH1A1MLKL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578573-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA Eiyo Ltd. (JP) | 2013-04-10 | — | — | EP | claimed |
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA EIYO LTD. (JP) | 2013-03-14 | — | — | US | claimed |
| US-9096531-B2 | Fused imidazole derivative | TOA EIYO LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| EP-2578573-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA Eiyo Ltd. (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA EIYO LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | CACNA1E, CACNA1G, CACNA1A | SCN10A 85/4885MEN1 2676/4885HTT 3959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.