SCHEMBL12070133

SCHEMBL12070133

CCCCOC[C@H]1O[C@@H](c2ccc(Cl)c(C3(C#N)CC3)c2)[C@H](OCCCC)[C@@H](OCCCC)[C@@H]1OCCCC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 11/20 0.33
▸ SSTR1 P30872 1/20 0.30
▸ SSTR2 P30874 1/20 0.30
▸ SSTR4 P31391 1/20 0.30
▸ SSTR3 P32745 1/20 0.30
▸ SSTR5 P35346 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12070129 0.83 SLC5A2 (0.34) SLC5A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL14841904 0.81 PTPN1 (0.38) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL12070132 0.81 SLC5A2 (0.40) SLC5A2
SCHEMBL2600396 0.81 SLC5A2 (0.40) SLC5A2
SCHEMBL2600480 0.81 SLC5A2 (0.40) SLC5A2
SCHEMBL14235766 0.77 SLC5A2 (0.41) SLC5A2
SCHEMBL2600479 0.77 SLC5A2 (0.45) SLC5A2
SCHEMBL14235767 0.77 SLC5A2 (0.45) SLC5A2
SCHEMBL14236379 0.77 SLC5A2 (0.45) SLC5A2
SCHEMBL12070130 0.77 SLC5A2 (0.41) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130090298-A1 Thiazole Derivatives as SGLT2 Inhibitors and Pharmaceutical Composition Comprising Same GREEN CROSS CORPORATION (KR) 2013-04-11 — — US disclosed
WO-2011159067-A2 THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME GREEN CROSS CORPORATION (KR) 2011-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130090298-A1 Thiazole Derivatives as SGLT2 Inhibitors and Pharmaceutical Composition Comprising Same SLC5A2, SLC5A1, SLC10A2 SLC5A2 1/4885SSTR1 2285/4885SSTR2 846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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