Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.38 |
| ▸ | CDC25B | P30305 | 8/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850077 | 0.84 | SLC5A2 (0.33) | — | |
| SCHEMBL14841444 | 0.83 | PTPN1 (0.41) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL12070133 | 0.81 | SLC5A2 (0.33) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL9983886 | 0.81 | HTR1A (0.39) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL2129656 | 0.81 | HTR1A (0.39) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL2130552 | 0.81 | HTR1A (0.39) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL9983888 | 0.81 | HTR1A (0.39) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL2130061 | 0.77 | HTR1A (0.41) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL22330760 | 0.77 | PTPN1 (0.45) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL20643059 | 0.77 | PTPN1 (0.43) | PTPN1CDC25BPTPN2PTPN11PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586550-B2 | Thiazole derivatives as SGLT2 inhibitors and pharmaceutical composition comprising same | GREEN CROSS CORPORATION (KR) | 2013-11-19 | — | — | US | disclosed |
| US-20130090298-A1 | Thiazole Derivatives as SGLT2 Inhibitors and Pharmaceutical Composition Comprising Same | GREEN CROSS CORPORATION (KR) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090298-A1 | Thiazole Derivatives as SGLT2 Inhibitors and Pharmaceutical Composition Comprising Same | SLC5A2, SLC5A1, SLC10A2 | PTPN1 179/4885CDC25B 3149/4885PTPN2 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.