Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12069893 | 1.00 | USP7 (0.50) | USP7NR1H4PLATMAOAMAOB | |
| SCHEMBL12505958 | 0.93 | USP7 (0.48) | USP7NR1H4PLATCNR1CNR2 | |
| SCHEMBL12070540 | 0.93 | USP7 (0.48) | USP7NR1H4PLATCHRM1CHRM3 | |
| SCHEMBL24844836 | 0.91 | USP7 (0.47) | USP7NR1H4PLATCNR1CNR2 | |
| SCHEMBL12506163 | 0.91 | USP7 (0.47) | USP7NR1H4PLATCNR1CNR2 | |
| SCHEMBL12255466 | 0.89 | NR1H4 (0.41) | USP7NR1H4PLATMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL19434241 | 0.85 | USP7 (0.43) | USP7NR1H4PLATCHRM1CHRM3 | |
| SCHEMBL3696393 | 0.78 | CNR1 (0.39) | USP7CNR1CNR2USP30GRM5 | |
| SCHEMBL3122755 | 0.78 | CNR1 (0.39) | MAOAMAOBCNR1CNR2USP30 | |
| SCHEMBL23624594 | 0.78 | CASP3 (0.51) | CNR1CNR2USP30GRM5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148922-A1 | NOVEL QUINAZOLINE COMPOUND | 田辺三菱製薬株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |