Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12506163 | 1.00 | USP7 (0.47) | USP7CNR1CNR2GRM5PLAT | |
| SCHEMBL12505958 | 0.98 | USP7 (0.48) | USP7CNR1CNR2GRM5PLAT | |
| SCHEMBL12070540 | 0.95 | USP7 (0.48) | USP7CNR1CNR2GRM5PLAT | |
| SCHEMBL12069893 | 0.91 | USP7 (0.50) | USP7CNR1CNR2GRM5PLAT | |
| SCHEMBL12070397 | 0.91 | USP7 (0.50) | USP7CNR1CNR2GRM5PLAT | |
| SCHEMBL23624594 | 0.89 | CASP3 (0.51) | CNR1CNR2GRM5CASP3SENP7 | |
| SCHEMBL12255466 | 0.81 | NR1H4 (0.41) | USP7GRM5PLATNR1H4 | |
| SCHEMBL3127019 | 0.81 | CNR1 (0.48) | CNR1CNR2GRM5CASP3SENP7 | |
| SCHEMBL15508611 | 0.81 | GRM5 (0.41) | CNR1CNR2GRM5PLATCASP3 | |
| Hydrochloric Acid SCHEMBL4229174 | 0.80 | GRM5 (0.40) | CNR1CNR2GRM5CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023275744-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | TECNIMEDE - Sociedade Técnico-medicinal, SA (PT) | 2023-01-05 | — | — | WO | disclosed |