Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 18/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14927046 | 0.92 | PTAFR (0.53) | PTAFRTHRBFYN | |
| SCHEMBL14926993 | 0.89 | PTAFR (0.51) | PTAFRTHRB | |
| SCHEMBL14930719 | 0.83 | FYN (0.40) | PTAFRTHRBFYN | |
| SCHEMBL14906859 | 0.82 | PTAFR (0.45) | PTAFRTHRBFYN | |
| SCHEMBL14903973 | 0.73 | PTAFR (0.40) | PTAFRTHRBFYN | |
| SCHEMBL9693418 | 0.73 | PTAFR (1.00) | PTAFR | |
| SCHEMBL10618457 | 0.70 | PTAFR (0.82) | PTAFR | |
| Hydrochloric Acid SCHEMBL10397113 | 0.69 | PTAFR (0.81) | PTAFR | |
| Hydrochloric Acid SCHEMBL10396468 | 0.69 | PTAFR (0.84) | PTAFR | |
| Hydrochloric Acid SCHEMBL9438229 | 0.69 | PTAFR (0.98) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
| WO-2011159926-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011156626-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | PTAFR 3790/4885THRB 2893/4885FYN 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.