Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206479 | 0.89 | CNR2 (0.51) | PDCD1CD274HTR7CTSACNR2 | |
| SCHEMBL410769 | 0.82 | PDCD1 (0.44) | PDCD1CD274PDK2PTPRCCNR2 | |
| SCHEMBL4108345 | 0.78 | PDCD1 (0.51) | PDCD1CD274PDE5APDE4APDE1A | |
| SCHEMBL2782523 | 0.77 | ALDH1A1 (0.56) | PDCD1CD274PDK2CYP3A4 | |
| SCHEMBL1206460 | 0.76 | RORC (0.40) | PDCD1CD274CTSACNR2RORC | |
| SCHEMBL20550345 | 0.72 | CYP1A1 (0.56) | PDCD1CD274HTR7PDK2PTPRC | |
| SCHEMBL6948272 | 0.72 | PDCD1 (0.46) | PDCD1CD274CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8023702 | 0.72 | PDCD1 (0.49) | PDCD1CD274CTSAESR1ESR2 | |
| SCHEMBL14128373 | 0.72 | ADORA2A (0.39) | PDCD1CD274PDK2HSD17B3RORB | |
| SCHEMBL1497158 | 0.72 | CYP2C19 (0.53) | PDCD1CD274HTR7PDK2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888365-B2 | Tri-aryl/heteroaromatic cannabinoids and use thereof | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2011-02-15 | — | — | US | claimed |