Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12074884 | 0.91 | PDGFRB (0.45) | CD274PDCD1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14903961 | 0.79 | PDCD1 (0.48) | CD274PDCD1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12074882 | 0.73 | PDGFRB (0.52) | CYP1A2CYP3A4CYP2D6LMNAUSP2 | |
| SCHEMBL12074762 | 0.71 | PDE10A (0.43) | CYP1A2CYP3A4CYP2D6LMNAUSP2 | |
| SCHEMBL14903970 | 0.70 | PDE10A (0.40) | CYP1A2CYP3A4CYP2D6LMNAUSP2 | |
| SCHEMBL12070517 | 0.69 | USP2 (0.44) | CD274PDCD1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12074044 | 0.69 | PDGFRB (0.72) | ALDH1A1PDGFRBPDGFRASMN1; SMN2MAPT | |
| SCHEMBL4477977 | 0.64 | CD274 (0.50) | CD274PDCD1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL27749171 | 0.64 | HPGD (0.64) | CD274PDCD1CYP1A2LMNAALOX15 | |
| SCHEMBL14903952 | 0.63 | PSMB5 (0.40) | CD274PDCD1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163610-A2 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-29 | — | — | WO | disclosed |