Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 9/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903952 | 0.84 | PSMB5 (0.40) | PDCD1CD274PSMB5TSHRALDH1A1 | |
| SCHEMBL12074884 | 0.81 | PDGFRB (0.45) | PDCD1CD274PSMB5TSHRALDH1A1 | |
| SCHEMBL12074760 | 0.79 | CD274 (0.40) | PDCD1CD274PSMB5TSHRALDH1A1 | |
| SCHEMBL14926984 | 0.77 | PDCD1 (0.47) | PDCD1CD274TSHRALDH1A1CYP1A2 | |
| SCHEMBL14903976 | 0.77 | PDCD1 (0.53) | PDCD1CD274PSMB5CYP1A2VSIR | |
| SCHEMBL14903970 | 0.75 | PDE10A (0.40) | TSHRALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL14903962 | 0.74 | CD274 (0.46) | PDCD1CD274 | |
| SCHEMBL14926982 | 0.68 | CD274 (0.45) | PDCD1CD274 | |
| SCHEMBL28019424 | 0.68 | PSMB5 (0.54) | PSMB5TSHRALDH1A1KDM4ECYP1A2 | |
| SCHEMBL358303 | 0.67 | CD274 (1.00) | PDCD1CD274ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | PDCD1 4650/4885CD274 4594/4885PSMB5 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.