Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 15/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906859 | 0.74 | PTAFR (0.45) | PTAFRDNMT1RAD52UHRF1SMARCA2 | |
| SCHEMBL9693616 | 0.66 | PTAFR (1.00) | PTAFREED | |
| SCHEMBL9694303 | 0.65 | PTAFR (1.00) | PTAFREED | |
| SCHEMBL5121302 | 0.65 | CA1 (0.66) | PTAFRDNMT1RAD52UHRF1CA1 | |
| SCHEMBL10810584 | 0.64 | CA1 (0.51) | PTAFRDNMT1RAD52UHRF1SMARCA2 | |
| Hydrochloric Acid SCHEMBL1697524 | 0.63 | CA1 (0.64) | PTAFRDNMT1RAD52UHRF1CA1 | |
| SCHEMBL8295470 | 0.62 | CA1 (0.54) | PTAFRCA1CA2CA4CA7 | |
| SCHEMBL29039568 | 0.61 | PTAFR (0.44) | PTAFRDNMT1RAD52UHRF1CA1 | |
| SCHEMBL1598936 | 0.61 | DNMT1 (0.43) | PTAFRDNMT1RAD52UHRF1EED | |
| SCHEMBL12797972 | 0.60 | PTGS2 (0.45) | PTAFRDNMT1RAD52UHRF1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
| WO-2011163610-A2 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | PTAFR 4433/4885DNMT1 3066/4885RAD52 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.