Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | PTAFR | P25105 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821213 | 0.84 | PTGS2 (0.50) | PTGS2CA1CA2CA4CA7 | |
| SCHEMBL12757506 | 0.81 | PTGS2 (0.41) | PTGS2CA1CA2CA4CA7 | |
| SCHEMBL20960631 | 0.74 | ALDH1A1 (0.58) | CA1CA2CA4CA7PTAFR | |
| SCHEMBL12757514 | 0.74 | PTGS2 (0.43) | PTGS2PTAFRGAAALDH1A1RECQL | |
| SCHEMBL5121302 | 0.73 | CA1 (0.66) | PTGS2CA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL1697524 | 0.72 | CA1 (0.64) | PTGS2CA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL12502728 | 0.70 | HDAC8 (0.56) | PTGS2CA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL12502636 | 0.68 | HDAC8 (0.42) | PTGS2CA1CA2CA4CA7 | |
| SCHEMBL8295470 | 0.67 | CA1 (0.54) | PTGS2CA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL12502639 | 0.67 | PTAFR (0.49) | PTAFRDNMT1RAD52UHRF1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902374-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| US-7902374-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| US-20070088167-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2007-04-19 | — | — | US | disclosed |
| US-20070088167-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2007-04-19 | — | — | US | disclosed |