Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 7/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393486 | 0.87 | MAOA (0.53) | CALML3MAOAMAOB | |
| SCHEMBL1393484 | 0.84 | CALML3 (0.42) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL1394095 | 0.79 | MAOA (0.57) | CALML3MAOAMAOB | |
| SCHEMBL1393696 | 0.79 | MAOA (0.53) | CALML3MAOAMAOB | |
| SCHEMBL1394094 | 0.75 | CALML3 (0.45) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL1394013 | 0.73 | MAOA (0.52) | CALML3MAOAMAOB | |
| SCHEMBL6092804 | 0.73 | CALML3 (0.59) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL6092806 | 0.73 | CALML3 (0.59) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL3095610 | 0.72 | MAOA (0.58) | CALML3MAOAMAOB | |
| SCHEMBL10266890 | 0.72 | MAOA (0.60) | CALML3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492264-A2 | Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same | Rib-X Pharmaceuticals, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |