Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.59 |
| ▸ | MAOA | P21397 | 7/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092806 | 1.00 | CALML3 (0.59) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL18786530 | 0.88 | CALML3 (0.63) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL6093515 | 0.88 | CALML3 (0.63) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL18790181 | 0.87 | CALML3 (0.62) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL1393478 | 0.85 | MAOA (0.65) | CALML3MAOAMAOB | |
| SCHEMBL18790221 | 0.82 | CALML3 (0.56) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL18770280 | 0.82 | CALML3 (0.56) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL20528030 | 0.80 | CALML3 (0.56) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL18770259 | 0.80 | MAOA (0.52) | CALML3MAOAMAOB | |
| SCHEMBL25759763 | 0.80 | MAOA (0.54) | CALML3MAOAMAOBCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270680-A1 | Sulfonamide compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270680-A1 | Sulfonamide compounds and methods of making and using the same | PCNA, SI, SQOR | CALML3 3744/4885MAOA 2626/4885MAOB 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.