Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | CALML3 | P27482 | 7/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16562190 | 0.91 | MAOA (0.45) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL16562185 | 0.83 | MAOA (0.47) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3088861 | 0.82 | MAOA (0.65) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394150 | 0.82 | MAOA (0.65) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL16562187 | 0.77 | MAOA (0.42) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL16562189 | 0.77 | MAOA (0.42) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL16559601 | 0.76 | CALML3 (0.43) | MAOACALML3MAOBBACE1 | |
| SCHEMBL4163852 | 0.75 | CALML3 (0.64) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL4163850 | 0.75 | CALML3 (0.64) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393956 | 0.74 | MAOA (0.67) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492264-A2 | Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same | Rib-X Pharmaceuticals, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |