Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12077492 | 0.92 | CNR1 (0.60) | CNR1CNR2ACHEPTGER4CYP1A2 | |
| SCHEMBL12077014 | 0.89 | PTGER4 (0.54) | CNR1CNR2ACHEPTGER4CYP1A2 | |
| SCHEMBL12077280 | 0.87 | F2RL3 (0.49) | CNR1CNR2ACHEPTGER4CYP1A2 | |
| SCHEMBL12076984 | 0.79 | F2RL3 (0.50) | CNR1CNR2ACHEPTGER4CYP1A2 | |
| SCHEMBL27923057 | 0.78 | CNR2 (0.64) | CNR1CNR2ACHEPTGER4CYP1A2 | |
| SCHEMBL12077272 | 0.77 | KMT2A (0.51) | CNR1CNR2ACHEPTGER4CYP1A2 | |
| SCHEMBL9917403 | 0.77 | CNR2 (0.81) | CNR1CNR2ACHEPTGER4CYP1A2 | |
| SCHEMBL3500587 | 0.77 | CYP1A2 (0.70) | CNR1PTGER4CYP1A2CYP2D6KDM4E | |
| SCHEMBL30493974 | 0.77 | CYP1A2 (0.70) | CNR1PTGER4CYP1A2CYP2D6KDM4E | |
| SCHEMBL2739310 | 0.75 | CNR2 (0.65) | CNR1CNR2ACHEPTGER4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2502916-B1 | ORGANIC DICARBOXYLIC ACIDS, SALTS AND PREPARATION METHOD THEREOF | UNIV SOUTHEAST (CN) | 2014-04-30 | — | — | EP | disclosed |
| US-8637677-B2 | Organic dicarboxylic acids, salts and preparation method thereof | SOUTHEAST UNIVERSITY (CN) | 2014-01-28 | — | — | US | disclosed |
| EP-2502916-A1 | ORGANIC DICARBOXYLIC ACIDS, SALTS AND PREPARATION METHOD THEREOF | Southeast University (CN) | 2012-09-26 | — | — | EP | disclosed |
| US-20120226051-A1 | ORGANIC DICARBOXYLIC ACIDS, SALTS AND PREPARATION METHOD THEREOF | SOUTHEAST UNIVERSITY (CN) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120226051-A1 | ORGANIC DICARBOXYLIC ACIDS, SALTS AND PREPARATION METHOD THEREOF | OTC, OGDH, SLC25A11 | CNR1 4322/4885CNR2 4368/4885ACHE 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.