Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12077492 | 0.91 | CNR1 (0.60) | PTGER4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL12077100 | 0.89 | CNR1 (0.52) | PTGER4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL12077272 | 0.88 | KMT2A (0.51) | PTGER4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL9186085 | 0.83 | CNR1 (0.58) | PTGER4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL11316855 | 0.80 | PTGER4 (0.71) | PTGER4CYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL9186092 | 0.80 | PTGER4 (0.56) | PTGER4CYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL12077280 | 0.76 | F2RL3 (0.49) | PTGER4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL2739310 | 0.74 | CNR2 (0.65) | PTGER4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL28757989 | 0.73 | CNR1 (0.63) | PTGER4CNR1ACHECNR2CYP1A2 | |
| SCHEMBL14288003 | 0.73 | PTGER4 (0.53) | PTGER4CNR1ACHECNR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2502916-B1 | ORGANIC DICARBOXYLIC ACIDS, SALTS AND PREPARATION METHOD THEREOF | UNIV SOUTHEAST (CN) | 2014-04-30 | — | — | EP | disclosed |
| US-8637677-B2 | Organic dicarboxylic acids, salts and preparation method thereof | SOUTHEAST UNIVERSITY (CN) | 2014-01-28 | — | — | US | disclosed |
| EP-2502916-A1 | ORGANIC DICARBOXYLIC ACIDS, SALTS AND PREPARATION METHOD THEREOF | Southeast University (CN) | 2012-09-26 | — | — | EP | disclosed |
| US-20120226051-A1 | ORGANIC DICARBOXYLIC ACIDS, SALTS AND PREPARATION METHOD THEREOF | SOUTHEAST UNIVERSITY (CN) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120226051-A1 | ORGANIC DICARBOXYLIC ACIDS, SALTS AND PREPARATION METHOD THEREOF | OTC, OGDH, SLC25A11 | PTGER4 4711/4885CNR1 4322/4885ACHE 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.