SCHEMBL1207987

SCHEMBL1207987

CCNc1ccc2c(c1)Sc1cc(NCC)ccc1N2C(C)=O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 3/20 0.50
▸ SNCA P37840 3/20 0.46
▸ BCHE P06276 7/20 0.43
▸ MAPT P10636 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ POLB P06746 2/20 0.40
▸ ATM Q13315 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29850631 1.00 NOX1 (0.50) NOX1SNCABCHEMAPTGAA
SCHEMBL30851251 0.83 NOX1 (0.54) NOX1SNCABCHEKDM4E
SCHEMBL1926804 0.83 NOX1 (0.54) NOX1SNCABCHEKDM4E
SCHEMBL10847578 0.81 NOX1 (0.53) NOX1SNCAMAPTPOLBKDM4E
SCHEMBL8223437 0.75 NOX1 (0.46) NOX1SNCABCHE
SCHEMBL19942820 0.74 BCHE (0.49) SNCABCHEMAPTGAANPSR1
SCHEMBL5452710 0.74 SNCA (0.73) NOX1SNCABCHEGAAPOLB
SCHEMBL29776881 0.74 SNCA (0.73) NOX1SNCABCHEGAAPOLB
SCHEMBL1208719 0.73 NOX1 (0.50) NOX1SNCABCHEMAPTPOLB
SCHEMBL29850616 0.73 NOX1 (0.50) NOX1SNCABCHEMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2025-10-23 — — US disclosed
US-12324810-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2025-06-10 — — US disclosed
US-20240245700-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2024-07-25 — — US disclosed
US-11951110-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2024-04-09 — — US disclosed
CN-109384741-B 3,7-diamino-10H-phenothiazine compound salt and application thereof 维斯塔实验室有限公司 2023-01-06 — — CN disclosed
CN-104606199-B 3, 7-diamino-10H-phenothiazine compound salt and use thereof 维斯塔实验室有限公司 2022-09-13 — — CN disclosed
US-11344558-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2022-05-31 — — US disclosed
US-20220152038-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2022-05-19 — — US disclosed
US-20190151329-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (SG) 2019-05-23 — — US disclosed
US-10188658-B2 Therapeutic use of diaminophenothiazines WISTA LABORATORIES LTD. (SG) 2019-01-29 — — US disclosed
US-8710051-B2 3,7-diamino-10H-phenothiazine salts and their use Wis Ta Laboratories Ltd. (SG) 2014-04-29 — — US disclosed
US-20110118242-A1 3,7-DIAMINO-10H-PHINOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. 2011-05-19 — — US disclosed
US-7888350-B2 3,7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2011-02-15 — — US disclosed
US-20100290986-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES Wis Ta Laboratories Ltd. 2010-11-18 — — US disclosed
EP-2013191-B1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LAB LTD (SG) 2010-08-18 — — EP disclosed
EP-2205245-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES Wista Laboratories Ltd. (SG) 2010-07-14 — — EP disclosed
WO-2009044127-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (GB) 2009-04-09 — — WO disclosed
US-20090054419-A1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. 2009-02-26 — — US disclosed
EP-2013191-A2 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE Wista Laboratories Ltd. (SG) 2009-01-14 — — EP disclosed
WO-2007110627-A2 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2007-10-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP NOX1 187/4885SNCA 673/4885BCHE 468/4885
US-12324810-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP NOX1 347/4885SNCA 467/4885BCHE 460/4885
US-20110118242-A1 3,7-DIAMINO-10H-PHINOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP NOX1 450/4885SNCA 1937/4885BCHE 260/4885
US-20100290986-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES QDPR, DDO, HNMT NOX1 2161/4885SNCA 447/4885BCHE 68/4885
US-11951110-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP NOX1 187/4885SNCA 673/4885BCHE 468/4885
US-10188658-B2 Therapeutic use of diaminophenothiazines QDPR, DDO, HNMT NOX1 2397/4885SNCA 430/4885BCHE 72/4885
US-11344558-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP NOX1 187/4885SNCA 673/4885BCHE 468/4885
US-20220152038-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP NOX1 255/4885SNCA 437/4885BCHE 350/4885
US-20190151329-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES QDPR, DDO, HNMT NOX1 2264/4885SNCA 398/4885BCHE 66/4885
US-20240245700-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP NOX1 347/4885SNCA 467/4885BCHE 460/4885
US-20090054419-A1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, HTT NOX1 490/4885SNCA 1049/4885BCHE 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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