Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Inogatran SCHEMBL22746 | 1.00 | F2 (0.52) | F2PRSS1F10PLGPLAT | |
| Inogatran SCHEMBL22745 | 1.00 | F2 (0.52) | F2PRSS1F10PLGPLAT | |
| Inogatran SCHEMBL6666022 | 0.99 | F2 (0.51) | F2PRSS1F10PLGPLAT | |
| SCHEMBL8409263 | 0.87 | F2 (0.45) | F2PRSS1F10PLGPLAT | |
| Inogatran SCHEMBL871973 | 0.87 | F2 (0.47) | F2PRSS1F10PLGPLAT | |
| SCHEMBL6665350 | 0.84 | PRCP (0.45) | F2PRSS1F10PLG | |
| SCHEMBL14082058 | 0.81 | F2 (0.62) | F2PRSS1F10PLGPLAT | |
| SCHEMBL5862690 | 0.76 | F2 (0.52) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13141174 | 0.76 | F2 (0.39) | F2PRSS1F10PLGPLAT | |
| SCHEMBL23793969 | 0.75 | F2 (0.75) | F2PRSS1F10PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110033474-A1 | INHIBITION OF PLATELET AGGREGATION | FITZGERALD DESMOND JOSEPH | 2011-02-10 | — | — | US | disclosed |
| US-20100041587-A1 | COMBINATION THERAPY FOR INHIBITION OF PLATELET AGGREGATION | PORTER R STEPHEN | 2010-02-18 | — | — | US | disclosed |
| US-20070082840-A1 | Combination therapy for inhibition of platelet aggregation | VDDI PHARMACEUTICALS | 2007-04-12 | — | — | US | disclosed |
| US-20060205764-A1 | Inhibition of platelet aggregation | VDDI PHARMACEUTICALS | 2006-09-14 | — | — | US | disclosed |
| WO-2005087266-A1 | COMBINATION THERAPY FOR INHIBITION OF PLATELET AGGREGATION | VDDI PHARMACEUTICALS (US) | 2005-09-22 | — | — | WO | disclosed |
| US-5980951-A | Oral coated active drugs | MERCK & CO., INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0914099-A1 | ORAL COATED ACTIVE DRUGS | Merck & Co., Inc. (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997037641-A1 | ORAL COATED ACTIVE DRUGS | MERCK & CO., INC. (US) | 1997-10-16 | — | — | WO | disclosed |