Inogatran

Inogatran

SCHEMBL22745

N=C(N)NCCCNC(=O)[C@@H]1CCCCN1C(=O)[C@@H](CC1CCCCC1)NCC(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F2 P00734 19/20 0.52
PRSS1 P07477 4/20 0.52
F10 P00742 1/20 0.46
PLG P00747 1/20 0.46
PLAT P00750 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Inogatran SCHEMBL22746 1.00 F2 (0.52) F2PRSS1F10PLGPLAT
Inogatran SCHEMBL1208039 1.00 F2 (0.52) F2PRSS1F10PLGPLAT
Inogatran SCHEMBL6666022 0.99 F2 (0.51) F2PRSS1F10PLGPLAT
SCHEMBL8409263 0.87 F2 (0.45) F2PRSS1F10PLGPLAT
Inogatran SCHEMBL871973 0.87 F2 (0.47) F2PRSS1F10PLGPLAT
SCHEMBL6665350 0.84 PRCP (0.45) F2PRSS1F10PLG
SCHEMBL14082058 0.81 F2 (0.62) F2PRSS1F10PLGPLAT
SCHEMBL5862690 0.76 F2 (0.52) F2PRSS1PRSS2PRSS3
SCHEMBL13141174 0.76 F2 (0.39) F2PRSS1F10PLGPLAT
SCHEMBL23793969 0.75 F2 (0.75) F2PRSS1F10PLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605371-B2 Combination therapy for cancer THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-04-21 US claimed
US-12521258-B2 Anticoagulant compounds and methods and devices for their use ELIXIR MEDICAL CORPORATION (US) 2026-01-13 US claimed
WO-2025262269-A1 MONITORING OF REVERSAL AGENTS FOR ANTICOAGULANTS ENZYRE B.V. (NL) 2025-12-26 WO claimed
US-20250177502-A1 THROMBIN AND FIBRINOGEN AS TARGETS FOR ATOPIC DERMATITIS DIAGNOSIS AND TREATMENT CHILDRENS HOSPITAL MED CT (US) 2025-06-05 US claimed
WO-2025019850-A1 COMPOSITIONS AND METHODS FOR REDUCING NANOPARTICLE-ASSOCIATED COAGULATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-01-23 WO claimed
US-20240424175-A1 ANTICOAGULANT COMPOUNDS COMPRISING CHELATING AGENTS AND CATIONIC ANTI-COAGULATION ENHANCERS AND METHODS AND DEVICES FOR THEIR USE ELIXIR MEDICAL CORPORATION (US) 2024-12-26 US claimed
WO-2024238703-A1 ANTICOAGULANT COMPOSITIONS COMPRISING ANTI-PLATELET AND ANTI-INFLAMMATORY DRUGS AND METHODS AND DEVICES FOR THEIR USE ELIXIR MEDICAL CORPORATION (US) 2024-11-21 WO claimed
EP-4463185-A2 THROMBIN AND FIBRINOGEN AS TARGETS FOR ATOPIC DERMATITIS DIAGNOSIS AND TREATMENT Children's Hospital Medical Center (US) 2024-11-20 EP claimed
US-20240277773-A1 COMPOSITION AND PROCESS FOR AN INFILTRATION AND TRANSPORT MEDIUM FOR ADIPOSE TISSUE CELLS UNIVERSITEIT GENT (BE) 2024-08-22 US claimed
US-20240189495-A1 METHODS OF PREPARING AN EXTRACORPOREAL CIRCUIT FOR ANTICOAGULATION LOWELL THERAPEUTICS, LLC 2024-06-13 US claimed
WO-2000041715-A1 NEW DIALYSIS METHOD ASTRAZENECA AB (SE) 2000-07-20 WO claimed
WO-2000012043-A1 IMPROVED STABILITY FOR INJECTION SOLUTIONS ASTRAZENECA AB (SE) 2000-03-09 WO claimed
EP-0942960-A1 PROMOTION OF REGENERATION OF ORGANIZED TISSUES Hansson, Hans-Arne (SE) 1999-09-22 EP claimed
CN-1219965-A Promoting regeneration of organotypic tissue HANS ARNE HANSSON (SE) 1999-06-16 CN claimed
CN-1213309-A Control of healing process HANSSON HANS ARNE (SE) 1999-04-07 CN claimed
EP-0874634-A1 CONTROL OF HEALING PROCESS Hansson, Hans-Arne (SE) 1998-11-04 EP claimed
WO-1998016252-A1 NEW PHARMACEUTICAL PARENTERAL FORMULATION OF A THROMBIN INHIBITOR ASTRA AKTIEBOLAG (SE) 1998-04-23 WO claimed
WO-1997039770-A1 NEW PHARMACEUTICAL FORMULATION OF A THROMBIN INHIBITOR FOR PARENTERAL USE ASTRA AKTIEBOLAG (SE) 1997-10-30 WO claimed
WO-1997037002-A1 PROMOTION OF REGENERATION OF ORGANIZED TISSUES HANSSON HANS ARNE (SE) 1997-10-09 WO claimed
WO-1997025994-A1 CONTROL OF HEALING PROCESS HANSSON HANS ARNE (SE) 1997-07-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605371-B2 Combination therapy for cancer BRAF, TFPI, HGFAC F2 39/4885PRSS1 311/4885F10 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.